Computational protocol: The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity

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Protocol publication

[…] The sequence of VPAC1 extracellular domain 1-142 aa (with signal peptide) and mature VPAC1 with 31-457 aa (without signal peptide) were submitted to the prediction of the potential modification on cysteines using the online service software, including lipid modification using GPS-Lipid (, S-nitrosylation using GPS-SNO (, plamitoylation using CSS-Palm (, sumoylation using GPS-SUMO (, and phosphorylation using GPS ( for qualitative and quantitative analysis. […]

Pipeline specifications

Software tools GPS-LIPID, GPS-SNO, CSS-Palm, GPS-SUMO
Application PTM analysis
Diseases Ovarian Neoplasms
Chemicals Camptothecin, Cysteine