Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 8
Release date: Aug 29 2007
Last update date: Jan 17 2013
Access: Public
Diseases: Epilepsy, Frontal Lobe
Dataset link INDUCTION OF PANCREATIC ISLET CELL DIFFERENTIATION BY THE NEUROGENIN-NEUROD CASCADE

Experimental Protocol


Mouse pancreatic ductal cells (mPAC cells) were infected with equal titers of recombinant adenoviruses encoding human Neurogenin3 (AdCMV-NEUROG3) or mouse NeuroD1 (AdCMV-NeuroD1), and 48 hrs later their transcriptomes were compared with that of control cells infected with an adenovirus encoding beta­galactosidase (beta-gal; AdCMV-Bgal) using cDNA microarrays. Differences in the activation patterns of the two transcription factors were then determined by comparing the fold-change (FC) values of the pair-wise hybridizations Neurog3/Bgal and NeuroD1/beta-gal.

Repositories


GEO

GSE7884

ArrayExpress

E-GEOD-7884

BioProject

PRJNA99919

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Contact


Michael German
Michael Scott German