Dataset features

Specifications


Application: RNA-seq analysis, BS-seq analysis
Number of samples: 12
Release date: May 20 2016
Last update date: Oct 10 2018
Access: Public
Diseases: Leukemia, Lymphoma
Computational protocol: GSEA, DAVID
Dataset link DNMT3A and TET2 Compete and Cooperate to Repress Differentiation Lineage-Specific Factors in Hematopoietic Stem Cells

Experimental Protocol


I)Whole genome bisulfite sequencing of Tet2 conditional knockout hematopoietic stem cells, Tet2 and DNMT3a double knockout hematopoietic stem cells using Illumina HiSeq 2000.II)Whole genome CMS-enriched bisulfite sequencing of Tet2 conditional knockout hematopoietic stem cells, Tet2 and DNMT3a double knockout hematopoietic stem cells using Illumina HiSeq 2000.III)Whole genome mRNA profiles of Tet2 conditional knockout hematopoietic stem cells, Tet2 and DNMT3a double knockout hematopoietic stem cells using Illumina HiSeq 2000. IV)Genome wide histone modification H3K27me3 profiling of Tet2 conditional knockout hematopoietic stem cells, Tet2 and DNMT3a double knockout hematopoietic stem cells using Illumina HiSeq 2000

Repositories


GEO

GSE72148

ENA

SRP062557

BioProject

PRJNA293214

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Contact


Jianzhong Su

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