Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 9
Release date: Nov 14 2016
Last update date: Oct 24 2018
Access: Public
Diseases: Leukemia, Myeloid, Acute
Chemicals: Daunorubicin, Anthracyclines
Genes: DNMT3A
Dataset link DNMT3A R882 mutations promote anthacyline resistance through impaired DNA-damage sensing [RNA-Seq]

Experimental Protocol


We have generated a novel genetic mouse model conditionally expressing mutant Dnmt3a from an endogenous locus and examined transcriptomes from FACS-sorted LSK populations from Dnmt3a+/+ (wt_Mx+), Dnmt3a+/m (cKI_Mx+), and Dnmt3a+/- (cKI_Cre-) animals at 6 months of age

Repositories


GEO

GSE72737

ENA

SRP063451

BioProject

PRJNA295055

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Contact


Barbara Spitzer