Computational protocol: Detection and analysis of circulating large intergenic non‐coding RNA regulator of reprogramming in plasma for breast cancer

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Protocol publication

[…] All statistical analyses were conducted using SPSS version 20.0 (IBM Corp., Armonk, NY, USA) and GraphPad Prism 5.0 (GraphPad Software, LaJolla, CA, USA). Data were presented with mean ± standard deviation (SD). Comparisons between two groups of continuous data with the Gaussian distribution were calculated by Student's t‐test, while comparison between two groups was calculated by Mann–Whitney U test. The Wilcoxon test was used to compare preoperative and postoperative plasma samples. Sigmaplot version 12.5 (Systat Software, San Jose, CA, USA) was used to run a logistic regression analysis in order to control for potential confounders, and receiver operating characteristic (ROC) curves of lincRNA‐ROR, CA15‐3, and CEA were established to differentiate BC patients from healthy controls. All tests were two‐sided and P < 0.05 was considered statistically significant. […]

Pipeline specifications

Software tools SPSS, SigmaPlot
Application Miscellaneous
Chemicals Estrogens