Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 7
Release date: Jun 1 2017
Last update date: Nov 20 2018
Access: Public
Diseases: Chemical and Drug Induced Liver Injury
Chemicals: Acetaminophen
Dataset link Ly6C high monocytes and their macrophage descendants regulate neutrophil function and clearance in acetaminophen-induced liver injury

Experimental Protocol


Neutrophils (defined as Ly6G+CD11b+Ly6Clo cells) were sorted at 24h following AILI from normal livers (n=4) or livers that are deficient for Ly6Chi infiltrating monocytes (n=3). RNA-seq based transcriptomicn profiling was performed to deliniate the effect of monocyte deficiency on nuetrophil activity and survival.

Repositories


GEO

GSE95182

ENA

SRP100513

BioProject

PRJNA376374

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Contact


Steffen Jung

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