|Number of samples:||7|
|Release date:||Jun 1 2017|
|Last update date:||Nov 20 2018|
|Diseases:||Chemical and Drug Induced Liver Injury|
|Dataset link||Ly6C high monocytes and their macrophage descendants regulate neutrophil function and clearance in acetaminophen-induced liver injury|
Neutrophils (defined as Ly6G+CD11b+Ly6Clo cells) were sorted at 24h following AILI from normal livers (n=4) or livers that are deficient for Ly6Chi infiltrating monocytes (n=3). RNA-seq based transcriptomicn profiling was performed to deliniate the effect of monocyte deficiency on nuetrophil activity and survival.
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