Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 12
Release date: Jan 4 2016
Last update date: Aug 13 2018
Access: Public
Diseases: Neoplasms, Cholangiocarcinoma, Brachydactyly
Dataset link Low-power photodynamic therapy induces survival signaling in cultured hilar cholangiocarcinoma cells

Experimental Protocol


Hilar cholangiocarcinoma (SK-ChA-1) cells were incubated with PBS (control group) or 500 μM zinc phthalocyanine (ZnPC)-encapsulating liposomes (ZnPC-ITLs, final lipid concentration). After 30 minutes, cells that were incubated with ZnPC-ITLs were either kept in the dark (ITL group) or were treated with 500-mW (ITL 500) or 50-mW (ITL 50) laser light (n = 3 per group, cumulative light dose of 15 J/cm2). Ninety minutes after photodynamic therapy, total cellular RNA was isolated and gene expression levels were analyzed by using the Illumina HumanHT-12 v4 platform. The data was analyzed in the context of survival signalling and comparisons were made with the control group.

Repositories


GEO

GSE68292

ArrayExpress

E-GEOD-68292

BioProject

PRJNA282388

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Contact


Perry Moerland
Perry D Moerland

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