|Application:||Gene expression microarray analysis|
|Number of samples:||10|
|Release date:||Sep 13 2012|
|Last update date:||May 11 2017|
|Diseases:||Myoclonic Cerebellar Dyssynergia|
|Dataset link||Expression of constitutively active FOXO3 in murine forebrain leads to a loss of neural progenitors|
We sought to determine the transcriptional differences in forebrains from E12.5 mice expressing a constitutively active alleleof FoxO3 under the control of the forebrain-specific CaMKIIa promoter. To this end two time-pregnant dams were sacrificed 12 days after the vaginal plug was detected, and the embryos were prepared. Visual staging of the embryos confirmed their age. Genotyping and luciferase measurements were performed in order to assess presence and acitivity of the transgenes.