Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 6
Release date: May 23 2015
Last update date: Aug 13 2018
Access: Public
Diseases: Leukemia, Lymphocytic, Chronic, B-Cell
Chemicals: Oxygen
Dataset link SLAMF1/CD150 regulates chemotaxis, autophagy and therapy responses in chronic lymphocytic leukemia patients

Experimental Protocol


Microarrays were performed comparing genetic signature of CLL-like Mec-1 cell line (constitutively SLAMF1+), transfected with a non-effective (scrambled) shRNA cassette (TR30013) used as control, and a Mec-1 variant generated silencing SLAMF1 gene using pGFP-V-RS construct for SLAMF1 shRNA (TG309422). For each cell line variants, grown in vitro in complete medium, three biological replicates were included in the chip.

Repositories


GEO

GSE69165

ArrayExpress

E-GEOD-69165

BioProject

PRJNA284685

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Contact


SILVIA DEAGLIO