Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 8
Release date: Nov 28 2018
Last update date: Nov 29 2018
Access: Public
Diseases: Immune System Diseases, Virus Diseases
Genes: Sfmbt
Taxon: Homo sapiens, Mus musculus, Yellow fever virus
Dataset link Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq)

Experimental Protocol


We isolated splenocytes from two NRG-HIS mice and two NFA2-HIS/Flt3LG mice at six-weeks post YFV-17D infection and sorted these cells by human CD45 (hCD45) or human CD33 (hCD33) expression. We ran parallel Seq-Well arrays for each sorted population, enabling both unbiased characterization of the relative abundances of all lymphocytes, as well as a deeper examination of the cellular diversity within the myeloid compartment.

Repositories


GEO

GSE119750

ENA

SRP161172

BioProject

PRJNA490177

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Contact


Alexander Ploss