Dataset features

Specifications


Application: Gene expression microarray analysis, miRNA array analysis
Number of samples: 39
Release date: Jul 15 2014
Last update date: Jul 31 2014
Access: Public
Diseases: Heart Failure, Muscular Diseases, Neoplasms, Wasting Syndrome
Dataset link Involvement of miRNAs in the regulation of muscle wasting during catabolic conditions

Experimental Protocol


To determine which miRNAs are relevant for the atrophic process, we performed miRNA expression profiles of muscles from different atrophic models (starvation, denervation and streptozotocin-induced diabetes). We checked whether there was a common signature of miRNA expression in different atrophying conditions and we found that every catabolic situation require a peculiar pattern of miRNA. We further focus on the condition of denervation and identified the most up-regulated miRNAs in this condition, miRNA-206 and miRNA-21.

Repositories


GEO

GSE51648

ArrayExpress

E-GEOD-51648

BioProject

PRJNA224203

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Contact


Gerolamo Lanfranchi

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