|Application:||SNP array data analysis|
|Number of samples:||56|
|Release date:||Oct 22 2007|
|Last update date:||Dec 22 2017|
|Diseases:||Adenocarcinoma, Pancreatic Neoplasms|
|Dataset link||Pancreatic cancer_Affymetrix 100K SNP arrays|
A total of 27 fresh-frozen PDAC tissue specimens were obtained surgically or at autopsy from Yamaguchi University School of Medicine, Japan. All the tissues were confirmed histologically by a pathologist. Tissue microdissection was manually performed to collect more than 90% of tumor cells in all cases and DNA was extracted using a DNA extraction kit (SepaGene). Reference DNA was obtained from lymphocytes of total 13 healthy volunteers (six males and seven females). To assess DNA copy number alterations and LOH, we used the Copy Number Analyzer for Affymetrix GeneChip® (CNAG, Ver2.0) software (Nannya et al. Cancer Res. 2005 Jul 15;65(14):6071-9). The following Samples were added to the Series after this study was published: PC5_Hind (GSM278031), PC5_Xba (GSM278032), PC11-Hind (GSM278043), and PC19_Hind (GSM278057). A supplementary file describing the clinical data of 28 microdissected PDAC samples is linked at the bottom of the Series.