Dataset features

Specifications


Application: Gene expression microarray analysis, miRNA array analysis
Number of samples: 29
Release date: Dec 31 2015
Last update date: Jan 9 2018
Access: Public
Diseases: Kidney Diseases
Dataset link An integrative analysis of renal miRNA- and mRNA-expression signatures in progressive chronic kidney disease [validation cohort]

Experimental Protocol


mRNA- and miRNA-profiling was performed in a discovery cohort (n=43) and in a validation cohort (n=29) of renal biopsy samples from human subjects with various proteinuric nephropathies. In the discovery cohort, miRNA-mRNA correlations were identified for those subjects who showed a progressive decline of renal function during follow up. These profiles were reproduced in the validation cohort.

Repositories


GEO

GSE60860

BioProject

PRJNA259678

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Contact


Michael Rudnicki