|Application:||Gene expression microarray analysis, miRNA array analysis|
|Number of samples:||29|
|Release date:||Dec 31 2015|
|Last update date:||Jan 9 2018|
|Dataset link||An integrative analysis of renal miRNA- and mRNA-expression signatures in progressive chronic kidney disease [validation cohort]|
mRNA- and miRNA-profiling was performed in a discovery cohort (n=43) and in a validation cohort (n=29) of renal biopsy samples from human subjects with various proteinuric nephropathies. In the discovery cohort, miRNA-mRNA correlations were identified for those subjects who showed a progressive decline of renal function during follow up. These profiles were reproduced in the validation cohort.