Dataset features


Dataset type: Expression profiling by RT-PCR, transcription profiling by RT-PCR, Transcriptome or Gene expression
Number of samples: 40
Release date: Aug 21 2013
Last update date: Nov 4 2013
Access: Public
Diseases: Carcinoma, Hepatocellular
Dataset link Applied Biosystems Human TaqMan Low Density Array (TLDA) in plasma samples from HCC cases and controls

Experimental Protocol

A hospital-based HCC case-control study including 20 HCC patients and 20 controls is conducted in Columbia University Medical Center (CUMC), which is approved by the Institutional Review Board. Cases were newly diagnosed HCC patients who were treated in the Hepatobiliary Oncology Clinics, CUMC, and examined pathologically. Controls were recruited from volunteers through the Research Recruitment and Minority Outreach (RRMO) core of Herbert Irving Comprehensive Cancer Center (HICCC). Flyers were placed at strategic locations around CUMC where hospital visitors and employees frequent or were handed out at inreach events at the hospital or at outreach events in the community. Interested participants were directed to contact the trained recruitment staff from the RRMO and given further information about participation. Interested participants were excluded from the control group if diagnosed for any kind of cancer or liver disease. Eligible controls were asked to fill out the same demographic and epidemiological questionnaire as HCC cases. In the current study, controls were matched with HCC cases on age (±5 yrs), gender (male/female) and ethnicities (Caucasian/Hispanic/African-American/Asian).










Jing Shen