Computational protocol: Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals

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Protocol publication

[…] The data were analysed using the Statistica software (Series1203b, version 6.1 for Windows, Statsoft®, USA), the SPSS software (version 12.0.1, for Windows, SPSS Inc., USA). All variables were analysed for the normal distribution by Kolmogorov-Smirnov test.The one-way ANOVA combined with a multiple-comparisons procedure (Scheffe multiple range test) was used to compare differences in means for both sCD14 and mCD14 and the unpaired Student's t-test was used to investigate differences in plasma sCD14 between genders within the three groups (MM, ZZ and SZ). The Student's t-test with correction for multiple comparisons was performed to evaluate the differences in CD14 mRNA expression level in MM, SZ and ZZ monocytes. Plasma AAT levels were analyzed by the Kruskal-Wallis method for comparisons between more than two groups, and if significant, groups were compared by using the Mann-Whitney U test and corrected for multiple comparisons (Bonferroni). Tests with p < 0.05 were considered to be significant and data are presented as mean ± SEM or SD. […]

Pipeline specifications

Software tools Statistica, SPSS
Application Miscellaneous
Organisms Homo sapiens