Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 10
Release date: Oct 12 2018
Last update date: Oct 13 2018
Access: Public
Diseases: Fibrocystic Breast Disease, Neoplasms, Encephalomyelitis, Western Equine
Dataset link Maternal Western-style diet alters the transcriptome of chemically induced mammary tumors in female offspring rats

Experimental Protocol


Pregnant Sprague-Dawley (SD) rats received control diet (CD) or Western-style diet (WD) from gestational days (GD) 12-20 and post-natal days (PND) 1-21. At weaning, the female offspring received CD until the end of the tumor bioassay. Female offspring 3 weeks old from both CD and WD groups received a single intraperitoneal dose of 50 mg/kg of N-Methyl-N-Nitrosourea (MNU) dissolved in phosphate-buffered saline acidified with acetic acid. At the end of study, the animals were euthanized and mammary tumors were removed and kept at -80°C for molecular analysis.

Repositories


GEO

GSE96520

BioProject

PRJNA378885

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Contact


Lucas Bidinotto