|Application:||Gene expression microarray analysis|
|Number of samples:||10|
|Release date:||Oct 12 2018|
|Last update date:||Oct 13 2018|
|Diseases:||Fibrocystic Breast Disease, Neoplasms, Encephalomyelitis, Western Equine|
|Dataset link||Maternal Western-style diet alters the transcriptome of chemically induced mammary tumors in female offspring rats|
Pregnant Sprague-Dawley (SD) rats received control diet (CD) or Western-style diet (WD) from gestational days (GD) 12-20 and post-natal days (PND) 1-21. At weaning, the female offspring received CD until the end of the tumor bioassay. Female offspring 3 weeks old from both CD and WD groups received a single intraperitoneal dose of 50 mg/kg of N-Methyl-N-Nitrosourea (MNU) dissolved in phosphate-buffered saline acidified with acetic acid. At the end of study, the animals were euthanized and mammary tumors were removed and kept at -80°C for molecular analysis.