Computational protocol: Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB

Similar protocols

Protocol publication

[…] ESEfinder [,], RESCUE-ESE [,] and PESXs server [,,] were used to search the APOB exon 27 sequence for putative exonic splicing enhancers. […]

Pipeline specifications

Software tools ESEfinder, RESCUE-ESE
Application WGS analysis
Organisms Homo sapiens
Diseases Hypobetalipoproteinemias
Chemicals Cholesterol, Oligonucleotides, Superoxides