Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 6
Release date: Sep 11 2012
Last update date: May 15 2017
Access: Public
Diseases: Glioblastoma, Neoplasms
Chemicals: Tyrosine
Dataset link MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib

Experimental Protocol


RNA was isolated from parental U87 (U87_EV) and MGMT-transfected U87 (U87_MGMT) triplicate. Pairwise gene expression differences were compared between the two cell lines. Features selected had more than 2-fold up-or down-regulated (P values of >05, unpaired Student’s t-test with Bonferroni multiple testing correction) were identified. Database for annotation, visualization, and integrated discovery23 was used to identify enriched gene ontology (GO) biological themes.24 The GO data mining was conducted at a term specificity level 3.25 The EASE score was set at 0.05 and the minimum number of genes in a category was 5.

Repositories


GEO

GSE40776

ArrayExpress

E-GEOD-40776

BioProject

PRJNA174869

Download