|Application:||Gene expression microarray analysis|
|Number of samples:||6|
|Release date:||Sep 11 2012|
|Last update date:||May 15 2017|
|Dataset link||MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib|
RNA was isolated from parental U87 (U87_EV) and MGMT-transfected U87 (U87_MGMT) triplicate. Pairwise gene expression differences were compared between the two cell lines. Features selected had more than 2-fold up-or down-regulated (P values of >05, unpaired Student’s t-test with Bonferroni multiple testing correction) were identified. Database for annotation, visualization, and integrated discovery23 was used to identify enriched gene ontology (GO) biological themes.24 The GO data mining was conducted at a term specificity level 3.25 The EASE score was set at 0.05 and the minimum number of genes in a category was 5.