|Application:||Gene expression microarray analysis|
|Number of samples:||12|
|Release date:||Nov 30 2012|
|Last update date:||Oct 29 2018|
|Diseases:||Prostatic Neoplasms, Brachydactyly|
|Dataset link||Expression data of EZH2-dependent genes in prostate cancer cell lines|
The androgen-dependent prostate cancer cell line LNCaP and the LNCaP-derived androgen-independent cell line LNCaP-abl (abl) were used for this study, as their transcription profiles strongly resemble that of clinical androgen-dependent and castration resistant prostate tumors, respectively. EZH2 was silenced by specific siRNAs in both cell lines, and total RNA was extracted and hybridized on Affymetrix microarrays.