Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 12
Release date: Nov 30 2012
Last update date: Oct 29 2018
Access: Public
Diseases: Prostatic Neoplasms, Brachydactyly
Dataset link Expression data of EZH2-dependent genes in prostate cancer cell lines

Experimental Protocol


The androgen-dependent prostate cancer cell line LNCaP and the LNCaP-derived androgen-independent cell line LNCaP-abl (abl) were used for this study, as their transcription profiles strongly resemble that of clinical androgen-dependent and castration resistant prostate tumors, respectively. EZH2 was silenced by specific siRNAs in both cell lines, and total RNA was extracted and hybridized on Affymetrix microarrays.

Repositories


GEO

GSE39452

ArrayExpress

E-GEOD-39452

BioProject

PRJNA170907

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Contact


Kexin Xu