|Application:||Gene expression microarray analysis|
|Number of samples:||12|
|Release date:||Mar 23 2012|
|Last update date:||May 3 2012|
|Dataset link||Transcriptional study of oxLDL-induced foam cell formation in WT and Atf3-/- murine bone marrow macrophages|
Twelve female mice (six Atf3-/-, and six WT control mice) were sacrificed at 8-12 weeks of age, and macrophages were derived from the femoral bone marrow using rhM-CSF. oxLDL was introduced into the medium for six samples (3 WT and 3 Atf3-/-) at 25 ug/mL on day seven, and after 24 h of incubation, RNA was isolated using Trizol. Labeled cRNA derived from the RNA samples was hybridized to Affymetrix Mouse Exon Array 1.0 ST GeneChips. Microarray data were processed using transcript-level probesets, and are in log2 scale.
Citations per year
The Journal of Experimental Medicine