|Application:||ChIP-seq analysis, RNA-seq analysis|
|Number of samples:||26|
|Release date:||Jan 22 2015|
|Last update date:||Oct 18 2018|
|Dataset link||Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity|
Genome-wide binding analysis of AR, TOP1, MRE11 in prostate cancer cell line LNCaP with or without 5alpha-dihydrotestosterone (DHT) treatment. Nascent RNA analysis by global nuclear run-on (GRO-seq) in LNCaP cells transfected with siRNA with or without DHT treatment. Distribution of transcriptionally engaged RNA Pol II in LNCaP cells with or without DHT treatment by precision nuclear run-on and sequencing (PRO-seq).
MICHAEL G ROSENFELD