Dataset features

Specifications


Application: ChIP-seq analysis, RNA-seq analysis
Number of samples: 26
Release date: Jan 22 2015
Last update date: Oct 18 2018
Access: Public
Diseases: Prostatic Neoplasms
Chemicals: Androgens, Dihydrotestosterone
Dataset link Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity

Experimental Protocol


Genome-wide binding analysis of AR, TOP1, MRE11 in prostate cancer cell line LNCaP with or without 5alpha-dihydrotestosterone (DHT) treatment. Nascent RNA analysis by global nuclear run-on (GRO-seq) in LNCaP cells transfected with siRNA with or without DHT treatment. Distribution of transcriptionally engaged RNA Pol II in LNCaP cells with or without DHT treatment by precision nuclear run-on and sequencing (PRO-seq).

Repositories


GEO

GSE63202

ArrayExpress

E-GEOD-63202

ENA

SRP049720

BioProject

PRJNA266983

Download


Contact


MICHAEL ROSENFELD
MICHAEL G ROSENFELD