|Application:||Gene expression microarray analysis|
|Number of samples:||24|
|Release date:||Dec 23 2016|
|Last update date:||Nov 9 2017|
|Dataset link||Genome-wide mapping of expression in WT and p63 mutant mouse mandibular prominences at E10-E13|
All experiments used mouse tissues from the B6.129S7-Trp63tm2Brd/J (generated by Mills et al., (1999)) and C57BL6/J strains (The Jackson Laboratory/JAX). We refer to mice with both copies of the mutant p63 allele as homozygote or p63-/-. The p63+/- samples represent B6.129S7-Trp63tm2Brd/J and p63-/- represent embryos from crosses of B6.129S7-Trp63tm2Brd/J x B6.129S7-Trp63tm2Brd/J mice. For each stage, p63-/- and p63+/- littermates were collected to minimize between-litter variation within each genotype. Also for each stage, three biological replicates (i.e., three embryos, each from a different litter) were assayed per genotype. Samples were not pooled between litters.