Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 320
Release date: Jul 19 2018
Last update date: Oct 29 2018
Access: Public
Diseases: Diabetic Nephropathies
Dataset link Innate immune activity differentiate subtypes in new onset Type 1 diabetes that predict duration of the post-onset partial remission and correlate with responsiveness to CTLA4-Ig treatment

Experimental Protocol


UPN727 cells were stimulated with CTLA4 treated patients (n=54) and placebo patients (n=20) plasma at baseline (BL), 3 month, 12 month and 24 month (total n=294 samples w/ 2 missing 3 month samples). Plus stimulated with our local Recent onset T1DM plasma (n=26). Gene expression analysis was perfromed in order to evaluate the transcriptional signature associated with T1D.

Repositories


GEO

GSE102234

BioProject

PRJNA397066

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Contact


Martin Hessner