|Application:||Gene expression microarray analysis|
|Number of samples:||6|
|Release date:||Aug 23 2016|
|Last update date:||Oct 29 2018|
|Diseases:||Kidney Diseases, Neoplasms, Germ Cell and Embryonal|
|Dataset link||APOL1 renal-risk variants induce mitochondrial dysfunction (Affymetrix 1)|
Global gene expression profiles were performed on HEK293 Tet-on G0, G1, G2 and empty vector cells with and without Dox induction using Illumina human HT-12 v4 arrays. Another independent gene expression array system, Affymetrix HTA 2.0, was used to verify the results of Illumina arrays. Pair-wise and pattern-based analyses were applied to detect the mostly impacted pathways due to overexpression and by APOL1 genotypes.