Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 6
Release date: Aug 23 2016
Last update date: Oct 29 2018
Access: Public
Diseases: Kidney Diseases, Neoplasms, Germ Cell and Embryonal
Chemicals: Doxycycline
Dataset link APOL1 renal-risk variants induce mitochondrial dysfunction (Affymetrix 1)

Experimental Protocol


Global gene expression profiles were performed on HEK293 Tet-on G0, G1, G2 and empty vector cells with and without Dox induction using Illumina human HT-12 v4 arrays. Another independent gene expression array system, Affymetrix HTA 2.0, was used to verify the results of Illumina arrays. Pair-wise and pattern-based analyses were applied to detect the mostly impacted pathways due to overexpression and by APOL1 genotypes.

Repositories


GEO

GSE85919

BioProject

PRJNA339759

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Contact


Lijun Ma