Computational protocol: Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

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Protocol publication

[…] Data were indexed and integrated using MOSFLM and were scaled using SCALA . Structures were phased by molecular replacement using PHASER with the coordinates of either the C. elegans model of inactive catalytic domain or the refined CaMKIIγ, respectively, as search models. Refinement was carried out using REFMAC5 employing appropriate geometric and non-crystallographic restraints. The models and structure factors have been deposited with PDB accession codes listed in . […]

Pipeline specifications

Software tools iMosflm, CCP4, REFMAC5
Applications Small-angle scattering, Protein structure analysis
Organisms Homo sapiens
Chemicals Adenosine Triphosphate, Calcium