Computational protocol: A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in a Cell-Specific Manner. Implications for Virus Evolution

Similar protocols

Protocol publication

[…] Minimum free energy secondary structures were predicted using the default parameters of RNAfold WebServer: http://rna.tbi.univie.ac.at/cgi-bin/RNAfold.cgi [...] Statistical analysis was performed with IBM SPSS Statistics 21. The normality of the data was analyzed by Shapiro-Wilk test. P-values relative to wt mRNAs were calculated using two-tailed Student’s t-test (data with normal distribution) or Mann-Whitney U-test (data with non-normal distribution). Data were considered significant if P<0.05 (*P<0.05; **P<0.01; ***P<0.001). […]

Pipeline specifications

Software tools RNAfold, SPSS
Applications Miscellaneous, RNA structure analysis
Organisms Sindbis virus, Homo sapiens, Sleeping disease virus
Diseases Infection