Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 189
Release date: Oct 1 2015
Last update date: Aug 9 2018
Access: Public
Diseases: Charcot-Marie-Tooth Disease, Diabetes Mellitus, Type 1, Meningioma
Dataset link Canakinumab treatment for recent-onset type 1 diabeties mellitus: a multicenter randomized, placebo-controlled trial

Experimental Protocol


Transcriptional signatures were induced in healthy cryopreserved human donor peripheral blood mononuclear cells (UPN727) through exposure to 40% subject serum in a 9 hour co-culture. Sixty-Three randomly selected subjects (43 Canakinumab treatment; 20 placebo treatment) were analysed blindedly to treatment assignment. The statistical significance of differential gene expression was determined through ANalysis Of VAriation (ANOVA) and false discovery rates (FDR) using Partek Genomics Suite 6.5.

Repositories


GEO

GSE68049

BioProject

PRJNA281636

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Contact


Martin Hessner