Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 32
Release date: Jul 12 2017
Last update date: Aug 9 2018
Access: Public
Diseases: Precursor Cell Lymphoblastic Leukemia-Lymphoma
Dataset link The HDAC inhibitor Panobinostat (LBH589) exerts in vivo anti-leukaemic activity against in MLL-rearranged Acute Lymphoblastic Leukaemia and involves the RNF20/RNF40/WAC – H2B ubiquitination axis

Experimental Protocol


Gene expression was measured using Affymetrix platform in 4 distinct cell lines treated or untreated in vitro with Panobinostat at 5 nM for 24 hours. Four independent biological replicates were carried out.

Repositories


GEO

GSE78234

BioProject

PRJNA312966

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Contact


Luca Trentin