|Application:||Gene expression microarray analysis|
|Number of samples:||32|
|Release date:||Jul 12 2017|
|Last update date:||Aug 9 2018|
|Diseases:||Precursor Cell Lymphoblastic Leukemia-Lymphoma|
|Dataset link||The HDAC inhibitor Panobinostat (LBH589) exerts in vivo anti-leukaemic activity against in MLL-rearranged Acute Lymphoblastic Leukaemia and involves the RNF20/RNF40/WAC – H2B ubiquitination axis|
Gene expression was measured using Affymetrix platform in 4 distinct cell lines treated or untreated in vitro with Panobinostat at 5 nM for 24 hours. Four independent biological replicates were carried out.