Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 10
Release date: Jun 23 2016
Last update date: Aug 23 2018
Access: Public
Diseases: Leukemia, Murine Acquired Immunodeficiency Syndrome, Hematologic Neoplasms
Mutations: p|SUB|R|882|H, p|SUB|G|12|D
Dataset link Expression profiling of murine leukemia stem cell (LSC) lines established ex vivo by coexpression of R882H-mutated DNMT3A and NRAS-G12D post treatment with Dot1l inhibitor (Microarray)

Experimental Protocol


Gene expression data were generated using Mouse Genome 430 2.0 Microarray (Affymetrix) for four independently derived RH-RAS LSC lines (termed as LSC RH-RAS #1, #2, #3 and #4), two RH-RAS LSC lines (LSC RH-RAS #1 and # 3) treated with 1 µM SGC0946 (a Dot1l-specific small-molecule inhibitor) for 4 days, one MLL-AF9-transformed progenitor line and three NUP98-JARID1A transformed progenitor lines.

Repositories


GEO

GSE71439

ArrayExpress

E-GEOD-71439

BioProject

PRJNA291209

Download


Contact


Rui Lu