|Application:||Gene expression microarray analysis|
|Number of samples:||7|
|Release date:||Oct 16 2006|
|Last update date:||Mar 16 2012|
|Dataset link||Modulation of gene expression in a human cell line caused by poliovirus, vacciniavirus and interferon|
A human cell culture was used to investigate the response to viral infections. The cells were incubated for 1 h with either poliovirus or vacciniavirus, washed and incubated for another 4 to 16 h. Total RNA from three parallel cell cultures were used for each time point and compared with mock infected cells. Interferon-alpha, at a concentration sufficient to inhibit poliovirus replication, was used to help single out genes that might be involved in viral defence.