Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 112
Release date: Oct 29 2014
Last update date: Apr 20 2018
Access: Public
Diseases: Arthritis, Rheumatoid, Neoplasms, Psoriasis, Arthritis, Psoriatic
Dataset link Gene expression of CD14+ cells from RA, PsA and PsO patients with Infliximab treatment

Experimental Protocol


Between April 2007 and June 2009, 31 patients with active RA, PsA and Ps who were naïve to anti-TNF agents, were recruited from the Faculty Rheumatology Clinics at the University of Rochester Medical Center after informed, written consent was obtained in a protocol approved by the Research Subjects Review Board at the University of Rochester Medical Center. Of the 31 subjects, 9 had active RA and 12 had PsA despite treatment with Disease Modifying Anti-Rheumatic Drugs (DMARDs). Also, 10 patients with extensive Ps (>5% BSA) documented by a dermatologist, were enrolled and they were examined by a rheumatologist to exclude the presence of inflammatory arthritis. Nineteen healthy controls were also recruited.

Repositories


GEO

GSE57383

ArrayExpress

E-GEOD-57383

BioProject

PRJNA246407

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Contact


Christopher Ritchlin

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