Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 17
Release date: Aug 14 2012
Last update date: Jan 12 2017
Access: Public
Diseases: Encephalitis, California, Infection
Dataset link Comparative transcriptomic analysis of acute host responses during 2009 pandemic H1N1 influenza infection in mouse, macaque, and swine (mouse dataset)

Experimental Protocol


The goal of this experiment was to use global gene expression profiling to understand mouse lung cellular responses to pandemic H1N1 influenza A/Californica/04/2009 virus infection. Six- to eight-week-old female BALB/c mice were anesthetized and inoculated with either 50 μl of phosphate-buffered saline (PBS; Mock) or with 10^6 pfu of pandemic H1N1 influenza A/California/04/2009 virus in a 50 μl volume, and whole lungs were collected at days 1, 3 and 5 post-inoculation. Lung samples from 9 animals for the infection group were used for array analysis, three animals per time point. Lung samples from 8 animals for the mock group were used for array analysis, three animals for the day 1 and 3 time points and 2 animals for the day 5 time point.

Repositories


GEO

GSE40091

ArrayExpress

E-GEOD-40091

BioProject

PRJNA172769

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Contact


Michael Katze
Richard Roy Green

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