Computational protocol: Machine learning identifies a compact gene set for monitoring the circadian clock in human blood

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Protocol publication

[…] Gene expression from the three microarray datasets was processed using MetaPredict [] (https://github.com/jakejh/metapredict), which maps probes to Entrez Gene IDs (where necessary, summarizing the expression of multiple probes using the median), performs intra-study normalization and log-transformation, and uses ComBat [] to perform cross-study normalization. The merged data of control samples from all three datasets consisted of 17,477 genes measured in 498 samples. […]

Pipeline specifications

Software tools MetaOmics, ComBat
Databases Gene
Application Gene expression microarray analysis
Organisms Homo sapiens