Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 8
Release date: Nov 27 2007
Last update date: Aug 31 2012
Access: Public
Diseases: Metabolic Diseases
Chemicals: Cholesterol, Phenobarbital
Dataset link Diet and phenobarbital affect cholesterol homeostasis and drug metabolism

Experimental Protocol


One group of mice was treated i.p. with 50 mg/kg of phenobarbital in vehicle (5% DMSO in corn oil). Untreated group was injected vehicle. Third group was 7 days on 1 % (w/w) cholesterol diet prior vehicle treatment. After 10 h animals were sacrificed and livers were stored. Pools of total RNA from two animals were mixed. Three pools of untreated and phenobarbital treated groups, and two pools of cholesterol diet group were co-hybridized with liver reference on Sterolgene v0 cDNA microarray. No dye-swaps were performed.

Repositories


GEO

GSE6447

ArrayExpress

E-GEOD-6447

BioProject

PRJNA98643

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