Computational protocol: Exploring the relationship between polymorphic (TG/CA)n repeats in intron 1 regions and gene expression

Similar protocols

Protocol publication

[…] We used the Database for Annotation, Visualization and Integrated Discovery (DAVID)[,] (http://david.abcc.ncifcrf.gov) to identify enriched GO [] (http://www.geneontology.org) or Protein ANalysis THrough Evolutionary Relationships (PANTHER)[] (http://www.pantherdb.org/pathway/) biological processes, as well as known pathways such as those maintained in the KEGG [] (http://www.genome.jp/kegg/), Biocarta (http://www.biocarta.com) and PANTHER [] databases among the genes containing long I1 (TG/CA)n repeats. Biological processes or pathways over-represented relative to the whole human genome (version hg16) were identified using Fisher's exact test (five hits or more, FDR < 0.05 after BH correction []). […]

Pipeline specifications

Software tools DAVID, PANTHER
Application Protein sequence analysis
Diseases Neoplasms
Chemicals Calcium