Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 44
Release date: Jul 1 2007
Last update date: Mar 16 2012
Access: Public
Diseases: Heart Failure, Cardiomyopathies, Myocardial Ischemia, Ventricular Dysfunction, Left, Ventricular Dysfunction
Dataset link Myocardial gene expression of hibernating and control tissue from patients with ischemic left ventricular dysfunction

Experimental Protocol


Methods: We compared in patients with advanced coronary artery disease and impaired left ventricular function the gene expression profile of myocardial biopsies from hibernating myocardium (n=5), as identified in PET by a mismatch between perfusion and glucose metabolism, with expression profiles of matched biopsies from remote myocardium. Gene-specific PCR of selected genes was used to validate our technical approach. Immunohistochemical staining was performed for one gene of specific interest.

Repositories


GEO

GSE4704

BioProject

PRJNA96755

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Contact


Thomas Nuehrenberg