A server for prediction of aggregation propensity in protein structures and rational design of protein solubility. In dynamic mode, A3D takes into account the flexibility of natural and designed polypeptides.
Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Bellaterra, Spain and University of Warsaw, Faculty of Chemistry, Warsaw, Poland
A3D funding source(s)
Ministerio de Economia y Competividad, Spain [BFU2013–44763 to S.V.]; SUDOE, INTERREG IV B, FEDER [SOE4/P1/E831to S.V.]; ICREA [ICREA Academia 2009 to S.V.]; Foundation for Polish Science TEAM project [TEAM/2011–7/6] co-financed by the EU European Regional Development Fund operated within the Innovative Economy Operational Program