Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 30
Release date: Oct 5 2011
Last update date: Jul 31 2017
Access: Public
Chemicals: Halogenated Diphenyl Ethers
Dataset link Expression data from PBDE treated rats at PND22 and Week 13

Experimental Protocol


There were a total of 6 groups and 5x replication for each group, for 30 total samples that were analyzed. The groups were (1) pup-male-CTL, (2) pup-female-CTL, (3) pup-male-PBDE, (4) pup-female-PBDE, (5) rat-male-CTL, (6) rat-male-PBDE. We generated the following pairwise comparisons using R/maanova: malePups(PBDE vs CTL), femalePups(PBDE vs CTL), maleRats(PBDE vs CTL), CTLpups(male vs female), PBDEpups(male vs female). We also performed ANOVA test for SEX-by-DOSE (pups) and AGE-by-DOSE (males). For pups, genes with an FDR≤1% were selected; for rats, genes with FDR < 5% were selected.

Repositories


GEO

GSE32156

ArrayExpress

E-GEOD-32156

BioProject

PRJNA147631

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