Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 11
Release date: Apr 1 2012
Last update date: Jul 26 2018
Access: Public
Diseases: Leukemia, Hairy Cell, Lymphatic Diseases, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Dataset link Engraftment of limited numbers of pediatric leukemia into NOD/SCID/IL2Rcg-null mice enables surrogate markers for clinical outcome

Experimental Protocol


In the present study, we thus engrafted NSG mice with 18 different pediatric B cell precursor ALL, AML and T-ALL samples and could demonstrate that NSG-derived blasts retained their leukemogenic profile with respect to immune-phenotype, chromosomal aberrations, transcriptome, flowcytometric- and PCR-minimal residual disease (MRD) marker expression.

Repositories


GEO

GSE35504

ArrayExpress

E-GEOD-35504

BioProject

PRJNA152311

Download