|Number of samples:||26|
|Release date:||Aug 31 2017|
|Last update date:||Nov 29 2018|
|Dataset link||Ebola virus glycoprotein variant with increased infectivity for human cells dominated the 2013-2016 outbreak|
We generated stocks of lentiviral vector bearing one the following three M-EBOV GPs: founder, A82V, and A82V/T230A. These viral stocks were used to challenge MDDCs from two healthy, anonymous human donors. Stimulated MDDCs were harvested at 1, 2, 4, and 6 hours after viral addition. Gene expression in M-EBOV GP challenged MDDCs was compared to a unstimulated control.