Computational protocol: Robust circadian clock oscillation and osmotic rhythms in inner medulla reflecting cortico-medullary osmotic gradient rhythm in rodent kidney

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Protocol publication

[…] For detecting rhythmicity, cycling analysis was performed by JTK_cycle from Metacycle package with options of minper = 22 and maxper = 26. To compare two groups (Bmal1 deficient mice and their wild type littermates) in Fig. , statistical analysis was performed by Two-tailed Student’s T-test. The P-value < 0.05 was considered statistically significant. The P-values indicated was determined by JTK_cycle otherwise noted. […]

Pipeline specifications

Software tools JTK_CYCLE, MetaCycle
Application Transcription analysis
Organisms Rattus norvegicus, Mus musculus
Chemicals Urea, Vasopressins