Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 36
Release date: Sep 11 2014
Last update date: Apr 18 2017
Access: Public
Chemicals: Sodium
Dataset link mRNA expression data from purified macrophages isolated from bronchoalveolar lavage fluid from either wild-type mice or Scnn1b-transgenic mice at post-natal days (PND) 0, 3, 10, and 42

Experimental Protocol


30 total macrophage samples were analyzed; three from each timepoint (postnatal day 0, 3, 10, and 42) for both wildtype and Scnn1b-transgenic mice grown in specific-pathogen-free facilities and from postnatal day 42 wildtype and Scnn1b-transgenic mice maintained in a germ-free facility. In our manuscript, we were most interested in changes between WT and Scnn1b-Tg mice, however, the data can also be used to evaluate changes in gene expression across time (postnatal day 0, 3, 10, and 42). This data can also be used to evaluate the differences in macrophage biology at postnatal day 42 when mice are grown in specific-pathogen-free versus germ-free environments.

Repositories


GEO

GSE47548

ArrayExpress

E-GEOD-47548

BioProject

PRJNA206055

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Contact


Hong Dang