Dataset features

Specifications


Application: BS-seq analysis
Number of samples: 8
Release date: Jun 14 2018
Last update date: Nov 27 2018
Access: Public
Diseases: Lung Neoplasms, Neoplasms, Ovarian Neoplasms
Chemicals: Cisplatin, Platinum
Genes: PRPF31
Dataset link An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells [BiSulfite-seq]

Experimental Protocol


A total of four cell lines were purchased from ATCC and ECACC (Sigma-Aldrich) and cultured as recommended. To analyze the changes in the transcriptome as a result of CDDP treatment, we established the CDDP-resistant variants of H23-R, H460-R, A2780-R and OVCAR3-R from the parental-sensitive variants H23, H460, A2780 and OVCAR3, after exposure to increasing doses of CDDP treatment in a time period of 6–18 months.

Repositories


GEO

GSE109317

ENA

SRP131087

BioProject

PRJNA430411

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