|Number of samples:||8|
|Release date:||Jun 14 2018|
|Last update date:||Nov 27 2018|
|Diseases:||Lung Neoplasms, Neoplasms, Ovarian Neoplasms|
|Dataset link||An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells [BiSulfite-seq]|
A total of four cell lines were purchased from ATCC and ECACC (Sigma-Aldrich) and cultured as recommended. To analyze the changes in the transcriptome as a result of CDDP treatment, we established the CDDP-resistant variants of H23-R, H460-R, A2780-R and OVCAR3-R from the parental-sensitive variants H23, H460, A2780 and OVCAR3, after exposure to increasing doses of CDDP treatment in a time period of 6â18 months.