Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 43
Release date: Dec 1 2010
Last update date: Mar 22 2012
Access: Public
Diseases: Virus Diseases, Coronavirus Infections
Dataset link Early gene expression events in ferrets in response to SARS coronavirus infection versus direct interferon-alpha2b stimulation

Experimental Protocol


In experiments with IFN-a2b, for peripheral blood, 15 ferrets were randomly allocated to 3 groups: Day 0, 5 ferrets (no IFN injection), day 1, 6 ferrets (injected), and day 2, 4 ferrets (injected). For lung necropsies of injected ferrets with IFN-a2b, we used 12 ferrets in 3 groups: 4 ferrets, day 0 (no IFN injection), 4 ferrets, day 1 (injected) and 4 ferrets, day 2 (injected). Experimental groups for SARS-CoV infection was as follows: For peripheral blood, 3 and 4 ferrets for day 0 (no infection) and day 2 (infection) respectively. For lung neceropsies, a total of 9 ferrets in 3 groups, each with 3 replicates for day 0 (no infection), day 1 (infection) and day 2 (infection).

Repositories


GEO

GSE22581

ArrayExpress

E-GEOD-22581

BioProject

PRJNA128405

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Contact


Longsi Ran