|Application:||Gene expression microarray analysis|
|Number of samples:||43|
|Release date:||Dec 1 2010|
|Last update date:||Mar 22 2012|
|Diseases:||Virus Diseases, Coronavirus Infections|
|Dataset link||Early gene expression events in ferrets in response to SARS coronavirus infection versus direct interferon-alpha2b stimulation|
In experiments with IFN-a2b, for peripheral blood, 15 ferrets were randomly allocated to 3 groups: Day 0, 5 ferrets (no IFN injection), day 1, 6 ferrets (injected), and day 2, 4 ferrets (injected). For lung necropsies of injected ferrets with IFN-a2b, we used 12 ferrets in 3 groups: 4 ferrets, day 0 (no IFN injection), 4 ferrets, day 1 (injected) and 4 ferrets, day 2 (injected). Experimental groups for SARS-CoV infection was as follows: For peripheral blood, 3 and 4 ferrets for day 0 (no infection) and day 2 (infection) respectively. For lung neceropsies, a total of 9 ferrets in 3 groups, each with 3 replicates for day 0 (no infection), day 1 (infection) and day 2 (infection).