Computational protocol: The Role of the 3′UTR Region in the Regulation of the ACVR1/Alk-2 Gene Expression

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Protocol publication

[…] Extensive bioinformatic analysis of ACVR1/Alk-2 3′UTR sequence was performed using different programs available on line. The conservation profile was obtained with the tools for comparative genomics of the VISTA genome Browser ( different programs were applied to identify putative sites for miRs: TargetScan5.1 (, PicTar ( miRBase (, and miRanda ( For each miR we have indicated the mirSVR score that ranks the efficiency of miRanda predicted binding sites () . We also used a program for AU-rich elements-containing sequence detection available at […]

Pipeline specifications

Software tools TargetScan, PicTar, MiRanda, mirSVR
Databases miRBase
Applications Phylogenetics, Genome data visualization
Diseases Myositis Ossificans