Detects m/z values of biological samples for high-resolution mass spectrometry (MS). AMDORAP allows to address the relationships between biological effects and cellular metabolites based on accurate m/z values. The tool can detect more accurate m/z values from raw data and provide the platform for metabolic fingerprinting. The m/z errors by AMDORAP are smallest, although the number of compared compounds might be not enough. The method should be indispensable as a starting point for comparative liquid chromatography (LC)-orbitrap analysis.