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ActionPotential specifications

Information


Unique identifier OMICS_22874
Name ActionPotential
Alternative names ApPredict, Action Potential prediction on line, AP-portal, ActionPotential-Portal
Interface Web user interface
Restrictions to use None
Input data A simple concentration-response curve.
Output data A summary graph.
Programming languages C++
License BSD 3-clause “New” or “Revised” License
Computer skills Basic
Stability Stable
Registration required Yes
Maintained Yes

Download


bitbucket.png

Documentation


Maintainers


  • person_outline Gary Mirams
  • person_outline Geoff Williams

Additional information


https://figshare.com/articles/Action_Potential_Prediction_Web_Portal_Documentation/1039436 https://bitbucket.org/gef_work/ap_predict_online http://apportal.readthedocs.io/en/latest/

Information


Unique identifier OMICS_22874
Name ActionPotential
Alternative names ApPredict, Action Potential prediction on line, AP-portal, ActionPotential-Portal
Software type Application/Script
Interface Graphical user interface
Restrictions to use None
Input data A simple concentration-response curve.
Output data A summary graph.
Operating system Unix/Linux
Programming languages C++
License BSD 3-clause “New” or “Revised” License
Computer skills Medium
Version 3.4
Stability Stable
Requirements
Chaste
Maintained Yes

Download


download.png

Versioning


No version available

Documentation


Maintainers


  • person_outline Gary Mirams
  • person_outline Geoff Williams

Additional information


https://figshare.com/articles/Action_Potential_Prediction_Web_Portal_Documentation/1039436 https://bitbucket.org/gef_work/ap_predict_online http://apportal.readthedocs.io/en/latest/

Publication for ActionPotential

ActionPotential citations

 (4)
library_books

Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock in mice

2017
eLife
PMCID: 5633343
PMID: 28930069
DOI: 10.7554/eLife.28377.016

[…] that preclude direct comparisons (e.g., homo vs. het comparison, wt background vs. littermates); however, while there was not a significant increase in mepsc frequency (leading to a conclusion that actionpotential firing underlies all difference) in the matikainen-ankey study, this may be due to reduced power in highly variable data e.g., matikainen-ankey detected a strong trend towards […]

library_books

Variations in CT determination of target volume with active breath co ordinate in radiotherapy for post operative gastric cancer

2016
PMCID: 4985190
PMID: 26654032
DOI: 10.1259/bjr.20150332

[…] ; 0.05 (two-sided) was considered statistically significant., the maximum dimensions from different observers and different ct scans were obtained. x and y indicated the field width and length of the ap portal and z indicated the anterior–posterior field extent of the left lateral portal. the average variations of the maximum dimension were 32.5, 22 and 16.24 mm, respectively. anova showed no sign […]

library_books

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

2014
J Pharmacol Toxicol Methods
PMCID: 4266452
PMID: 25087753
DOI: 10.1016/j.vascn.2014.07.002

[…] ‘traditional’ fixed time step solvers for numerically stiff systems such as cardiac action potential models. the software is a custom-made program based on the open-source chaste library () and its appredict (action potential prediction) module., for the interested reader we have made the following resources available: the ic50 datasets, the action potential simulation software; and the scripts […]

library_books

Intra and inter radiation therapist reproducibility of daily isocenter verification using prostatic fiducial markers

2006
PMCID: 1436003
PMID: 16722575
DOI: 10.1186/1748-717X-1-2

[…] this threshold were reduced to 3 mm, 2.4% of table shifts would be due to observer error., a very small but statistically significant difference was found in observer variability between lateral and ap portal image manual matches (ap mean 0.8 mm [ci 0.75–0.84], llat mean 1 mm [ci 0.94–1.1], p < 0.01)., this technique has now been clinically applied in 166 consecutive treatments in 6 patients. […]


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ActionPotential institution(s)
Computational Biology, Dept. of Computer Science, University of Oxford, Oxford, UK
ActionPotential funding source(s)
Supported by an EPSRC and NC3Rs Mathematics in Toxicology Strategic Award (NC/K001337/1), an EPSRC Impact Acceleration Account Award (EP/K503769/1) and by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 101222/Z/13/Z).

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