ADAN

[…] This retrospective study was performed at Al-Bahar Ophthalmology Center and the Department of Ophthalmology at Al-Adan Hospital. Both institutions are part of the Ministry of Health, Kuwait. The Ethics Committee of Al-Bahar Ophthalmology Center approved this study. All efforts were made to adhere to the guideline […]

[…] CESS () program. In these calculations we used a probe radius of 1.4 Å and the program default sets of atomic radii and polarity. The corresponding ΔC°P values were calculated using a relation ΔC°P = aΔAN + bΔAP where a = (0.45 ± 0.02) cal mol−1 K−1 Å−2 and b = (−0.26 ± 0.02) cal mol−1 K−1 Å−2, () which appears to be appropriate for describing ΔC°P of ligand–DNA association (,). […]

[…] escriptors, Standardizer [] for structure normalization, and R [] for model building and validation. eTOXlab incorporates an in-house developed, highly efficient, implementation of PLS, and our novel ADAN method [] for assessing the applicability domain and providing reliability indexes for the predictions. However, this VM is only a basic configuration and modelers can install additional software […]

[…] nt (), and the selected strategy of SVM- and machine-learning-based epitope prediction known as CBTOBE (chapter 3; []). The same accuracy levels were rarely achieved in certain subsets when employing ADAN, KinasePhos 2.0 (), ElliPro, RANKPEP (), SVM and machine-learning-based epitope prediction improved by evolutionary information BEOracle (chapter 3; []) and docking tool HADDOCK (chapter 4; []). […]

[…] hage display experiments.The growth in the number of protein complexes with a determined 3D structure has facilitated the development of structural tools to predict SLiM specificities (; ; ; ; ). The ADAN database () utilizes the FoldX algorithm () to perform an assessment of the stability and affinity of peptide–domain complexes under in silico mutagenesis analysis. However, the requirement for e […]

[…] Pyrosequencing yielded high coverages of the BV-associated G. vaginalis strain, 5-1 (accession number: ADAM00000000) and the healthy subject isolate, AMD (accession number: ADAN00000000) genomes (~175X and ~130X, respectively). The data for both genomes assembled into approximately 20 contigs greater than 500 bp. Both genomes were estimated at approximately 1.65 Mb. In a […]