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ADNI specifications


Unique identifier OMICS_04620
Alternative name Alzheimer’s Disease Neuroimaging Initiative
Restrictions to use None
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Michael W. Weiner

Publication for Alzheimer’s Disease Neuroimaging Initiative

ADNI citations


Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer’s disease

Sci Rep
PMCID: 5945611
PMID: 29748598
DOI: 10.1038/s41598-018-25377-w

[…] We pooled MCI subjects from ADNI-1 and ADNI-2 studies. Sex-differences in baseline demographic and cognitive variables were tested using either analysis of variance (ANOVA) or analysis of covariance (ANCOVA).Next we ran three mi […]


A Neuroimaging Web Services Interface as a Cyber Physical System for Medical Imaging and Data Management in Brain Research: Design Study

PMCID: 5945984
PMID: 29699962
DOI: 10.2196/medinform.9063

[…] ion can vary among different hardware and software platforms. Hence, for this proposed Web interface, the RSs are calibrated, making sure they always provide the same results before their deployment. ADNI renders FreeSurfer results calculated on FreeSurfer 5.1. In order to validate NWSI, a paired t test was performed to compare the values reported in the ADNIMerge file and the NWSI results. A tota […]


Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment

PMCID: 5945969
PMID: 29761124
DOI: 10.1002/acn3.560

[…] s revealed a significant association between expression and genotype (effect size = 0.12, P = 0.004) in whole blood. We checked the relationship between APOE4 carrier status and GRN expression in the ADNI dataset but failed to detect a difference in GRN expression between APOE4 carriers and controls (T (613) = 1.43, P = 0.15). We also performed the converse analysis in the UCSF‐MAC cohort. Using C […]


Memory concerns in the early Alzheimer's disease prodrome: Regional association with tau deposition

PMCID: 5956937
PMID: 29780876
DOI: 10.1016/j.dadm.2018.03.001
call_split See protocol

[…] Preprocessed [18F]flortaucipir PET scans were downloaded from the ADNI Laboratory of Neuro Imaging (LONI; site. These scans were preprocessed using standard techniques in Statistical Parametric Mapping 8 (SPM8), including normalization to M […]


Classification of Alzheimer's and MCI Patients from Semantically Parcelled PET Images: A Comparison between AV45 and FDG PET

PMCID: 5875062
PMID: 29736165
DOI: 10.1155/2018/1247430

[…] r goal was to uncover which radiotracer demonstrated the stronger diagnostic accuracy and come to a recommendation of the tracer to use for AD. While both FDG and AV45 images were indeed available in ADNI for research purposes, typically in a clinical examination, FDG and AV45 will not be acquired during the same session, but rather one or the other. In a subsequent study, we will investigate the […]


Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Sci Rep
PMCID: 5841319
PMID: 29515158
DOI: 10.1038/s41598-018-21568-7

[…] In our study, we used 77 subjects (41 AD and 36 LMCI) from ADNI GO public dataset, each with structural T1-w MR image. Data used in the preparation of this article were obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database (adni.loni.u […]


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ADNI institution(s)
Department of Radiology, University of California, San Francisco, CA, USA

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