This is a highly refined terminology for coding clinical information in relation to drug therapy. WHO-ART covers most medical terms needed in adverse reaction reporting, but is still small enough to make it possible to print it out as a list which makes it easily usable for smaller companies and national centres.
A comprehensive ADR ontology database that provides not only ADR standardization but also hierarchical classification of ADR terms. The ADR terms were pre-assigned with unique digital IDs and at the same time were well organized into a four-level ADR hierarchy tree for building an ADR-ADR relation. In summary, ADReCS offers an opportunity for direct computation on ADR terms and also provides clues to mining common features underlying ADRs.
A rich and highly specific standardised medical terminology to facilitate sharing of regulatory information internationally for medical products used by humans. ICH’s powerful tool, MedDRA is available to all for use in the registration, documentation and safety monitoring of medical products both before and after a product has been authorised for sale.
A Web-based platform for collecting and storing toxicological structural alerts from literature and for virtual screening of chemical libraries to flag potentially toxic chemicals and compounds that can cause adverse side effects. An alert is uniquely identified by a SMARTS template, a toxicological endpoint, and a publication where the alert was described. Additionally, the system allows storing complementary information such as name, comments, and mechanism of action, as well as other data.
Gathers literature-based, manually curated associations between chemicals, gene products, phenotypes, diseases, and environmental exposures. CTD is a public resource aiming to advance the understanding about chemical exposures and human health. The database provides more than 38 million toxicogenomic relationships, as well as analysis tools. Users can explore novel connections and generate testable hypotheses about the molecular mechanisms of chemical influenced health outcomes.